PLACENTA-ASSOCIATED PLASMA PROTEIN AND FREE HUMAN CHORIONIC GONADOTROPIN LEVELS IN DAY 3 VERSUS DAY 5 TRANSFER

Aim: This study was conducted to investigate placenta-associated plasma protein (PAPP-A) and free human chorionic gonadotropin (B-hCG) levels after blastocyst transfer versus cleavage-stage embryo transfer. 
 Materials method: A total of 449 women were included in this rerospective sudy. The consisted two groups: Group 1: pregnant conceived by intracytoplasmic sperm injection (ICSI) procedures fresh at the cleavage stage (day 2 or day 3) had first trimester fetal aneuploidy biochemical markers performed 11-14th gestational week (n: 275). 2: ICSI 5) (n:174). Demographic characteristics, causes infertility, duration stimulation protocol regimens, doses, number follicles oocytes retrieval, endometrial thickness, fundus –embryo distance recorded measured. Results: We found no significant differences PAPP-A B-hCG levels, protocols regimens thickness fundus-embryo distance. Diminished ovarian reserve doses significiantly higher group 1 (p < 0.05). Number follicles, retrieval MII Conclusion: No difference observed between 3rd 5th